Urinary Biomarker in Bladder Cancer at Present Time
نویسندگان
چکیده
منابع مشابه
Urinary APE1/Ref-1: A Potential Bladder Cancer Biomarker
Bladder cancer (BCa) is one of the most common urothelial cancers with still noticeable incidence rate. Early detection of BCa is highly correlated with successful therapeutic outcomes. We previously showed that apurinic/apyrimidinic endonuclease 1/redox factor-1 (APE1/Ref-1) was expressed at an increased level in the serum of BCa patients when compared to the level in healthy controls. In this...
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OBJECTIVES Many markers for the detection of bladder cancers have been tested. Almost all urinary markers reported are better than cytology with regard to sensitivity, but they score lower in specificity. The purpose of this review is to highlight the most important urinary biomarkers studied and reported recently. METHODS Literature on bladder cancer markers has been reviewed regularly in th...
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Several drugs have shown in vitro and in vivo pharmacological activity against urinary bladder cancer. This review aims at compiling the different drugs evaluated in in vitro and in vivo models of urinary bladder cancer and to review the advantages and limitations of both types of models, as well as the different methodologies applied for evaluating antineoplastic drug activity. Cancer is one o...
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Bladder cancer occurs after the fifth decade and more frequently in men than in women (sex ratio 2:1 to 3:1). It has been associated mainly with smoking, but also with occupational exposure to carcinogens from aniline dyes, paints, rubber, etc, and chronic irritation of the bladder mucosa due to bladder stones, or schistosomiasis. The main symptom is painless hematuria, which in the adult patie...
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ژورنال
عنوان ژورنال: The Korean Journal of Urological Oncology
سال: 2020
ISSN: 2234-4977,2233-5633
DOI: 10.22465/kjuo.2020.18.3.183